Faculty profile headshot photo of Jack Saddler

Jack Saddler

Professor
NSERC Industrial Senior Chair

Forest Sciences Centre 4043
2424 Main Mall
Vancouver, BC V6T 1Z4
Canada

work phone: 604-822-9741

Research Areas:

Areas of research include:

  • Application of enzymes in enhancing pulp and fibre properties (e.g., NFC, NCC, etc.)
  • Biorefinery
  • Co-processing and use of low carbon intermediates in refineries
  • Biojet and other low carbon intensity fuels for long distance transport
  • IEA BioEnergy Task 39 (www.Task39.org)
  • Fibre modification and enhancing the properties of pulps
  • Bioconversion of lignocellulosic residues to biofuels
  • Microbiology of waste water treatment
  • Application of fungi to upgrading and modification of forest products, pulp and paper and waste streams

Projects

IEA bioconversion task, Biotechnology for the conversion of lignocellulosics

International Energy Agency

Biomass recalcitrance, the use of enzymes and their component- parts to better elucidate cellulose amorphogenesis and fiber structure

NSERC

Evaluation of domestic and international policy mechanisms to facilitate the establishment of a renewable drop-in/aviation/marine biofuel supply chain in Canada

BFN/NCE

Chemi-mechanical pretreatments for maximizing conversion, recovery and fractionation

BFN/NCE

A Bio-refinery approach to obtaining maximum chemical/biofuel value from Canadian biomass

Korea Institute Of Science & Tech

Developing facile methods to measure dissolving pulp reactivity based on the accessibility of cellulose chains

NSERC

Enzymatic modification of cellulose filaments for rheology applications

NSERC

Upgrading cellulose filaments for incorporation into value-added products

MITACS

Enzymatic hydrolysis of wheat straw derived xylo-oligomers stream into monomeric sugars

MITACS

Bioprocessing Centre for Sustainable Fuels

CFI

CFI Infrastructure Operating Funds – Bioprocessing Centre for Sustainable Fuels – Operations

CFI

The Potential to Repurpose Canadian Pulp Mills Into Biorefineries

BFN/NCE

Assessment of likely Technology Maturation pathways used to produce biojet from forest residues (ATM project)

GARDN

Chemi-mechanical pretreatments for maximizing conversion, recovery and fractionation

Novozymes

Incorporation of nanocellulose into thermoplastics for producing lightweight composite materials

BCIC

Enhancing dissolving pulp production and co-product value

NSERC CRD

Enhancing Dissolving Pulp Production and Co-product Value

Fortress Global Enterprises Inc. (NSERC Industry partner)

Assessing the suitability of an enzymatic pretreatment for enhancing refining effectiveness and surface modification during the production of nanofibrillated celluloses.

NSERC CRD

Assessing the suitability of an enzymatic pretreatment for enhancing refining effectiveness and surface modification during the production of nanofibrillated celluloses.

Various Industries (NSERC partner-PBF, Novozymes, Polyscope)


Awards

LifeSciences BC Leadership Award 2009
Fellow of the Royal Society of Canada 2007
Advances in Science and Technology Award, US Dept. of Agriculture, Peoria Illinois 2000
IUFRO Scientific Achievement (given out every 5 years) 1999
Charles D. Scott Awards for Scientific/Technical Contributions to Biotechnology for the Production of Fuels and Chemicals 1998
Green Fuels Industry Leadership Award 2015
Johannes Linneborn Prize 2016

Selected Publications

Seiji Nakagame, Yuta Shimizu, Jack N. Saddler (2020). The Production of Lipids Using 5-Hydorxymethy Furfural Tolerant Rhodotorula graminis Grown on the Hydrolyzates of Steam Pretreated Softwoods Sustainability 12/755
Jie Wu, Richard P. Chandra, Kwang Ho Kim, Chang Soo Kim, Yunqiao Pu, Arthur J. Ragauskas, Jack Saddler (2020). Enhancing Enzyme-Mediated Hydrolysis of Mechanical Pulps by Deacetylation and Delignification Sustainable Chemistry & Engineering
Kwang Ho Kim, Yunxuan Wang, Masatsugu Takada, Aymerick Eudes, Chang Geun Yoo, Chang Soo Kim, Jack Saddler (2020). Deep Eutectic Solvent Pretreatment of Transgenic Biomass With Increased C6C1 Lignin Monomers Frontiers in Plant Science 10, 1774/1-11
Susan van Dyk, Jianping Su, James McMillan, Jack (John) Saddler (2019). Potential synergies of drop-in biofuel production with further co-processing at oil refineries. Biofuels, Bioproducts, Biorefining SCI
Kevin Aïssa, Muzaffer A. Karaaslan, Scott Renneckar, Jack N. Saddler (2019). Functionalizing Cellulose Nanocrystals with Click Modifiable Carbohydrate-Binding Modules Biomacromolecules 20 (8), 3087-3093
Chaoran Meng, Na Zhong a, Jinguang Hu, Chongwen Yu, Jack N. Saddler (2019). The effects of metal elements on ramie fiber oxidation degumming and the potential of using spherical bacterial cellulose for metal removal Journal of Cleaner Production 498-507
Richard P. Chandra, Jie Wu, and Jack N. Saddler (2019). The Application of Fiber Quality Analysis (FQA) and Cellulose ACS Sustainable Chem. Eng 7, 8827−8833
Kevin Aïssa, Muzaffer A. Karaaslan, Scott Renneckar, and Jack N. Saddler (2019). Functionalizing Cellulose Nanocrystals with Click Modifiable Bio Macromolecules
Yanliang Song, Richard P. Chandra, Xu Zhang, Tianwei Tana, Jack N. Saddler (2019). Comparing a deep eutectic solvent (DES) to a hydrotrope for their ability to enhance the fractionation and enzymatic hydrolysis of willow and corn stover Sustainable Energy Fuels 3,1329-1337
Jie Wu, Richard Chandra, Jack Saddler (2019). Alkali-oxygen treatment prior to the mechanical pulping of hardwood enhances enzymatic hydrolysis and carbohydrate recovery through selective lignin modification Sustainable Energy The Royal Society of Chemistry
Na Zhong, Richard Chandra, John N. Saddler (2019). Sulfite post-treatment to simultaneously detoxify and improve the enzymatic hydrolysis and fermentation of a steam pretreated softwood lodgepole pine whole slurry Sustainable Chemistry & Engineering ACS
Kevin Aissa, Vera Novy, Fredrik Nielsen, John N. Saddler (2018). Use of carbohydrate binding modules to elucidate the relationship between fibrillation, hydrolyzability and accessibility of cellulosic substrates. Sustainable Chemistry & Engineering ACS
Jianguang Hu, Yiu Ki Mok, John N. Saddler (2018). Can we reduce the cellulase enzyme loading required to achieve efficient lignocellulose deconstruction by only using the initially absorbed enzymes? Sustainable Chemistry & Engineering ACS Publications
Yong Tang, Richard Chandra, Shahab Sokhansanj, Jack Saddler (2018). Influence of steam explosion process on the durability and enzymatic digestibility of wood pellets. Fuel Elsevier
Timo van der Zwan, Jinguang Hu, Jack Saddler (2017). Mechanistic insights into the liquefaction stage of enzyme-mediated biomass deconstruction Biotechnology and Bioengineering
S. Malgasa, R. Chandra, J.S. Van Dyk, J.N. Saddler, B.I. Pletschkea (2017). Formulation of an optimized synergistic enzyme cocktail, HoloMix, for effective degradation of various pre-treated hardwoods Bioresource Technology
Daniela Correia Martino, Jorge Luiz Colodette, Richard Chandra, Jack Saddler (2017). Steam explosion pretreatment used to remove hemicellulose to enhance the production of a eucalyptus organosolv dissolving pulp. Springer
S Karatzos, JS van Dyk, JD McMillan, J Saddler (2017). Drop‐in biofuel production via conventional (lipid/fatty acid) and advanced (biomass) routes. Part I - Biofuels, Bioproducts and Biorefining) Wiley
Yong Tang, Xiaoli Dou, Jinguang Hu, Jianxin Jiang, J Saddler (2017). Lignin sulfonation and SO2 addition enhance the hydrolyzability of deacetylated and then steam-pretreated poplar with reduced inhibitor formation Applied Biochem Biotechnology
Dong Tian, Jinguang Hu, Jie Bao, Richard Chandra, Jack N. Saddler, Canhui Lu (2017). Lignin valorization: lignin nanoparticles as high-value bio-additive for multifunctional nanocomposites. Biomed Central DOI 10.1186/s13068-017-0876-z
S. Van Dyk, J Saddler (2017). Flying Green. Policy recommendation for development of production and consumption of biojet fuels in Canada Bio Fuel Network
Richard Chandra, Qiulu Chu, Jinguang Hu, Na Zhong, Mandy Lin, Jin-Suk Lee, Jack Saddler (2016). The influence of lignin and mechanical pulping of poplar to achieve high sugar recovery and ease of enzymatic hydrolysis. 2015 Elsevier
Rui Zhai, Jinguang Hu, Jack N. Saddler (2016). What Are the Major Components in Steam Pretreated Lignocellulosic Biomass That Inhibit the Efficacy of Cellulase Enzyme Mixtures? ACS Sustainable Chemical Engineering
William Cadham, J.Susan Van Dyk, J.S. Linoj Kumar, Jack N. Saddler (2016). Chapter 7. Challenges and Opportunities for the Conversion Technologies Used to Make Forest Bioenergy Elsevier
Jinguang Hu, Amadeus Pribowo, Jack N. Saddler (2016). Oxidative cleavage of some cellulosic substrates by Auxiliary Activity (AA) Family 9 enzymes influences the adsorption/desorption of hydrolytic cellulase enzymes Royal Society of Chemistry
Fubao Fuebiol Sun, Jiapeng Hong, Jinguang Hu, Jack Saddler, Xu Fang, Zhenyu Zhang, Song Shen (2015). Accessory enxymes influence cellulase hydrolysis of the model substrate and the realistic lignocellulosic biomass Elsevier
B Dhillon, N Feau, A Aerts, S Beauseigle, L Bernier, A Copeland, A Foster, N Gill, B Henrissat, P Herath, K LaButti, A Levasseur, E Lindquist, E Majoor, R Ohm, J Pangilinan, A Pribowo, J Saddler, M Sakalidis, R de Vries, I Grigoriev, S Goodwin, P Tanguay, R Hamelin (2015). Horizontal gene transfer and gene dosage drives adaptation to wood colonization in a tree pathogen PNAS
Jinguang Hu, Keith Gourlay, Valdeir Arantes, J. S. Van Dyk, Amadeus Pribowo, Jack N. Saddler (2015). The Accessible Cellulose Surface Influences Cellulase Synergism during the Hydrolysis of Lignocellulosic Substrates Wiley DOI : 10.1002/cssc.201403335
Richard Chandra, Valdeir Arantes, Jack Saddler (2015). Steam pretreatment of agricultural residues facilitates hemicellulose recovery while enzyme accessibility to cellulose Elsevier
Colin Olsen, Valdeir Arantes, Jack Saddler (2015). Optimization of chip size and moisture content to obtain high, combined sugar recovery after sulfur dioxide-catalyzed steam pretreatment of softwood and enzymatic hydrolysis of the cellulosic component Elsevier
Yiu Ki Mok, Valdeir Arantes, Jack Saddler (2015). A NaBH2 coupled ninhydrin-based assay for the quantification of protein/enzymes during the enzymatic hydrolysis of pretreated lignocellulosic biomass Applied Biochemistry Biotechnology
Richard Chandra, Keith Gourlay, Chang Soo Kim, Jack Saddler (2015). Enhancing hemicellulose recovery and the enzymatic hydrolysis of cellulose by adding lignosulfonates during the two-stage steam pretreatment of poplar ACS Sustainable Chemistry & Engineering
Colin Olsen, Valdeir Arantes, Jack Saddler (2015). Optiomization of chip size and moisture content to obtain high, combined sugar recovery after sulfur dioxide-catalyzed steam pretreatment of softwood and enzymatic hydrolysis of the cellulosic component Bioresource Technology
Jinguang Hu, Richard Chandra, Valdeir Arantes, Keith Gourlay, J. Susan Van Dyk, Jack N. Saddler (2015). The addition of accessory enzymes enhances the hydrolytic perfromance of cellulose enzymes at high solid loadings Bioresource Technology
Richard Chandra, Qiulu Chu, Jinguang Hu, Na Zhong, Mandy Lin, Jin-Suk Lee, Jack Saddler (2015). Accessory enxymes influence cellulase hydrolysis of the model substrate and the realistic lignocellulosic biomass Elsevier
Stephen, J.D., Mabee, W.E., Saddler, J.N. (2014). The ability of cellulosic ethanol to compare for feedstock and investment with other forest bioenergy options Industrial Biotechnology
Keith Gourlay, Jinguang Hu, Valdeir Arantes, Merja Penttila, Jack N Saddler (2014). The use of Carbohydrate Binding Modules (CBMs) to monitor changes in fragmentation and cellulose fibre surface morphology during Cellulase and Swollenin induced deconstruction of lignocellulosic substrates The journal of Biological Chemistry
Valdeir Arantes, Keith Gourlay and Jack N. Saddler (2014). The enzymatic hydrolysis of pretreated pulp fibers predominantly involves "peeling/erosion" modes of action Biotechnology for Biofuels
Jinguang Hu, Valdeir Arantes, Amadeus Pribowo, Keith Gourlay and Jack N. Saddler (2014). Substrate factors that influence the synergistic interaction of AA9 and cellulases during the enzymatic hydrolysis of biomass Energy & Environmental Science
Arthur J. Ragauskas,* Gregg T. Beckham, Mary J. Biddy, Richard Chandra, Fang Chen, Mark F. Davis, Brian H. Davison, Richard A. Dixon, Paul Gilna, Martin Keller, Paul Langan, Amit K. Naskar, Jack N. Saddler, Timothy J. Tschaplinski, Gerald A. Tuskan, Charles E. Wyman (2014). Lignin Valorization: Improving Lignin Processing in the Biorefinery AAAS
Teresita Marzialetti, Juan Pablo Salazar, Constanza Ocampos, Richard Chandra, Pablo Chung, Jack Saddler, Carolina Parra (2014). Second-generation ethanol in Chile: optimisation of the autohydrolysis of Eucalyptus globulus Biomass Conversion and Biorefinery DOI 10.1007/s13399-014-0114-x
Hu J, Arantes V, Pribowo A & Saddler JN (2013). The synergistic action of accessory enzymes enhances the hydrolytic potential of a "cellulase mixture" but is highly substrate specific Biotechnology for Biofuels 6: 112
Gourlay, K., Hu, J., Arantes, V., Andberg, M., Saloheimo, M., Penttilä, M., Saddler, J., (2013). Swollenin Aids in the Amorphogenesis Step during the Enzymatic Hydrolysis of Pretreated Biomass Bioresource Technology (2013), 142, 498-503
Panagiotopoulos, I.A., Chandra, R.P., Saddler, J.N. (2013). A two stage pretreatment approach to maximise sugar yield to enhance reactive lignin recovery from poplar wood chips. Bioresource Technology, 130, 570–577
Kapu, S.L., Piddocke, M., Saddler, J.N. (2013). High gravity and high cell density mitigate some of the fermentation inhibitory effects of softwood hydrolysates AMB Express (2013). 3:15 doi: 10.1186/2191-0855-3-15
Saddler, J.N., Kumar, L. (2013). Special Issue from the NSERC Bioconversion network workshop: pretreatment and fractionation of biomass for biorefinery/biofuels Biotechnology for Biofuels 2013, 6:17
Pan XJ, Saddler J.N. (2013). Effect of replacing Polyol by organosolv and kraft lignin on the property and structure of rigid polyurethane foam Biotechnology for Biofuels 2013, 6:12
Saddler JN, Kumar L, Arantes V. Chandra R (2012). The lignin present in steam pretreated softwood binds enzymes and limits cellulose accessibility. -Bioresource Technology, 103:201-208
Saddler JN, Arantes V, Pribowo A (2012). The absorption and enzyme activity profiles of specific Trichoderma reesei Cellulase/Xylanase components when hydrolyzing steam pretreated corn stover. Enzyme and Microbial Technology, 50:195-203
Saddler, J.N. Mabee, Warren E. Simms, Ralph and Taylor, Michael. (2012). The Biorefining Story: Progress in the Commercialization of Biomass-to-Ethanol T. Schlichter and L. Montes ( eds.), Forests in Development: A Vital Balance, DOI 10.1007/978-94-007-2576-8_4, Springer Science +Business Media B.V. 2012 page 39-51.
Saddler JN, Gourlay K, Arantes V. (2012). Use of substructure-specific carbohydrate binding modules to track changes in cellulose accessibility and surface morphology during the amorphogenesis step of enzymatic hydrolysis. -Biotechnology for Biofuels, 5:51.
Fei Shen , Jinguang Hu, Yuehua Zhong , Michael L.Y. Liu , Jack N. Saddler Ronghou Liu (2012). Ethanol production from steam-pretreated sweet sorghum bagasse with high substrate consistency enzymatic hydrolysis -Biomass and Bioenergy 2012 ( 1-8)
Luis F. Del Rio, Richard P. Chandra, Jack N. Saddler (2012). The ease of Enzymatic hydrolysis of Organosolv-pretreated softwoods -Bioresource Technology 107(2012) 235-242
Saddler, J.N. Del Rio, Luis F. Chandra, Richard (2012). Fibre size does not appear to influcence the ease of enzymatic hydrolysis of organosolv-pretreated softwoods. -Bioresource Technology 107(2012) 235-242.
Olsen C, Arantes V, Saddler J.N. (2012). The use of predictive models to optimize sugar recovery obtained after the steam pretreatment of softwoods Biofuels, Bioproducts & Biorefining, 6:534-548.
Kumar Linoj, Saddler JN, Arantes Valdeir, Chandra Richard (2012). The lignin present in steam pretreated softwood binds enzymes and limites cellulose accessibility -Bioresource Technology Volume 103, Issue 1, Page 201-208.
Mabee Waren, Saddler JN, Stephen James D. (2011). Will Second-Generation Ethanol be able to compete with First-Generation Ethanol? Opportunities for cost reduction DOI: 10.1002/bbb.331; Biofuels, Bioprod. Bioref. (2011)
Chandra, RP, Au-Yeung K, Chanis C, Roos AA, Mabee W, Chung PA, Ghatora S, and Saddler, J. N. (2011). The Influence of Pretreatment and Enzyme Loading on the Effectiveness of Batch and Fed-Batch Hydrolysis of Corn Stover -Biotechnology Progress 2011. Volume 27 Issue 1, pages 77-85
Del Rio L, Chandra R.P, Saddler J.N. (2011). The Effects of Increasing Swelling and Anionic Charges on the Enzymatic Hydrolysis of Organosolv-preatreated Softwoods at Low Enzyme Loadings. --Biotechnology and Bioengineering Volume 108, issue 7, page 1549-1558
Nakagame S, Chandra R.P., Saddler J.N (2011). The influence of lignin on the enzymatic hydrolysis of pretreated biomass substrates. -Sustainable Production of Fuels, Chemicals, and Fibers from Forest Biomass. American Chemical Society. Chapter 6, page 145-167 ACS Symposium Series Volume 1067.
Nakagame S, Chandra R.P., Kadla J.F., Saddler J.N. (2011). The isolation, characterization and effect of lignin isolated from steam pretreated Douglas-fir on teh enzymatic hydrolysis of cellulose. -Bioresource Technology ( 2011) 102, 4507-4517
Arantes, V. and Saddler, J.N. (2011). Cellulose accessibility limits the effectiveness of minimum cellulase laoding on the efficient hydrolysis of pretreated lignocellulosic substrates -Biotechnology for Biofuels 4:3
Nakagame, S., Chandra, R., Kadla, J.F., Saddler, J. (2011). Enhancing the enzymatic hydrolysis of lignocellulosic biomass by increasing the carboxylic acid content of the associated lignin - Biotechn Bioeng 108, 538-548
Hu Jinguang, Arantes Valdeir, Saddler JN (2011). The enhancement of enzymatic hydrolysis of lignocellulosic substrates by the addition of accessory enzymes such as xylanase: is it an additive or synergistirc effect? -Biotechnology for Biofuels 2011 4:36
Kumar Linoj, Chandra Richard, Saddler JN (2011). Influence of steam pretreatment severity on post-treatments used to enhance the enzymatic hydrolysis of pretreated softwoods at low enzyme loadings. -Biotechnology and Bioengineering. Vol.108(10): 2300-2311.
Shen, F., Kumar, L., Hu, J., Saddler, J. N. (2011). Evaluation of hemicellulose removal by Xylanase and delignification on SHF and SSF for bioethanol production with steam-pretreated substrates. -Bioresource Technology, doi: 10.1016/j.biortech.2011.07.028
Sims, R.E.H., Mabee, W., Saddler, J.N. and Taylor, M. (2010). An overview of second generation biofuel technologies -Bioresource Technology Volume 101 issue 6, page 1570-1580
Tu, M.B. and Saddler, J.N. (2010). Potential enzyme cost reduction with the addition of surfactant during the hydrolysis of pretreated softwood -Applied Biochemistry and Biotechnology 161 (1-8): 274-287
Arantes, V. and Saddler, J.N. (2010). Access to cellulose limits the efficiency of enzymatic hydrolysis: the role of amorphogenesis -Biotechnology for Biofuels, 3:4, 1-11
Stephen, James D., Mabee, Warren E., Saddler, Jack N. (2010). Biomass logistics as a determinant of second-generation biofuel facility scale, location and technology selection -Biofpr, Biofuels Bioproducts & Biorefining 2010, DOI:10.1002/bbb.239;4:503-518 (2010)
Kumar, L., Chandra, R. P., Chung, P.A., Saddler, J. N. (2010). Can the same steam pretreatment conditions be used for most softwoods to achieve good, enzymatic hydrolysis and sugar yields? Bioresource Technology 2010; 101:7827-7833
Mabee, W., Sadder, J. N. (2010). Bioethanol from lignocellulosics: Status and perspectives in Canada -Bioresource Technology2010; 101:4806-4813
Nakagame, S., Chandra, R. P. and Saddler, J. N. (2010). The effect of isolated lignins, obtained from a range of pretreated lignocellulosic substrates, on enzymatic hydrolysis -Biotechnol Bioeng. 2010 Apr 1;105(5):871-9
Del-Rio, L.F., Chandra, R. P., and Saddler, J. N. (2010). The effect of varying organosolv pretreatment chemicals on the physiochemical properties and cellulolytic hydrolysis of mountain pine beetle killed lodgepole pine Applied Biochemistry and Biotechnology 2010; 161:1-21
Ackom, E., Mabee, W., Saddler, J. N. (2010). Industrial Sustainability of Competing Wood Energy Options in Canada Applied Biochemistry Biotechnology 2010 ( In Press)
Del Rio, L and Saddler, J.N. (2009). The Effect of Varying Organosolv Pretreatment Chemicals on the Physicochemical Properties and Cellulolytic Hydrolysis of Mountain Pine Beetle – killed Lodgepole Pine -Applied Biochemistry and Biotechnology Part A: Enzyme Engineering and Biotechnology, Article 8786
Tu, M.B., Pan, X.J., Saddler, J.N. (2009). Adsorption of Cellulase on Cellulolytic Enzyme Lignin from Lodgepole Pine -Journal of Agricultural and Food Chemistry 57 (17):7771–7778
Tu, M.B., Zhang, X., Paice, M., McFarlane, P.; Saddler, J.N. (2009). The Potential of Enzyme Recycling during the Hydrolysis of a Mixed Softwood Feedstock -Bioresource Technology 100(24):6407-6415
Tu, M.B., Zhang, X., Paice, M., McFarlane, P.; Saddler, J.N. (2009). Effect of Surfactants on Separate Hydrolysis Fermentation and Simultaneous Saccharification Fermentation of Pretreated Lodgepole Pine -Biotechnology Progress 25(4):1122-1129
Bura, R., Chandra, R. and Saddler, J.N. (2009). The influence of xylan on the enzymatic hydrolysis of steam pretreated corn stover and hybrid poplar -Biotechnology Progress 25(2):315-322
Chandra, R.P., Ewanick, S.M., Chung, P.A., Au-Yeung, K., Del Rio, L.. Mabee, W. & Saddler, J.N. (2009). Comparison of methods to assess the enzyme accessibility and hydrolysis of pretreated lignocellulosic substrates -Biotechnol Lett 31:1217-1222
Zhang, X., Qin, W., Paice, M.G. and Saddler, J.N. (2009). High consistency enzymatic hydrolysis of hardwood substrates -Bioresource Technology 100:5890-5897
Keating, J., Johansson, C.I., Saddler, J.N. and Beatson, R.P. (2008). Kinetics of hydrogen peroxide brightening of western red cedar (Thuja plicata Donn) CTMP -Journal of Wood Chemistry and Technology, 28(2):153-166
Pan, X-J, Xie, D., Yu, R.W. and Saddler, J.N. (2008). The bioconversion of mountain pine beetle-killed lodgepole pine to fuel ethanol using the organosolv process --Biotechnology and Bioengineeering, 101(1):39-48
Chandra, R.P., Ewanick, S.M., Hsseih, C. and Saddler, J.N. (2008). The characterization of pretreated lignocellulosic substrates prior to enzymatic hydrolysis part 1: A modified Somons' staining procedure -Botechnology Progress, 24(5):1178-1185
Munoz, C., Menoca, R., Baeza, j., Berlin, A., Saddler, J.N. and Freer, J. (2007). Bioethanol production from bi-organosolv pulps of Pinus radiata and Acacia dealbata -Journal of Chemical Technology & Biotechnology, 82(8):767-774
Pan, X.J., Xie, D., Kang, Y., Yoon, S.L. and Saddler, J.N. (2007). Effect of organosolv ethanol pretreatment variables on physical characteristics of hybrid poplar substrates -Applied Biochemistry and Biotechnology 136-140:367-378
Chandra, R.P., Bura, R., Mabee, W., Berlin, A., Pan, X. an Saddler, J.N. (2007). Substrate Pretreatment: The Key to Effective Enzymatic Hydrolysis of Lignocellulosics? -Special Volume of Advances in Biochemical Engineering/Biotechnology DOI 10.1007/10_2007_064
Tu, Maobing, Chandra, R. and Saddler, J.N. (2007). Evaluating the Distribution of Cellulases and the Recycling of Free Cellulases during the Hydrolysis of Lignocellulosic Subtrates -Biotechnology Progress Publlication 23(2):398-406
Chandra, R.P., Esteghalilan, A.R., and Saddler, J.N. (2007). Assessing Substrate Accessibility to Enzymatic Accessibility of Enzymatic Hydrolysis by Celulases -Book Chapter in American Chemical Society Book
Chandra, R.P., Beatson, R.P. and Saddler, J.N. (2007). Treatment of Douglas-fir Heartwood TMP with Laccases: Effect of Treatment Conditions on Peroxide Bleaching -Journal of Wood Chemistry and Technology 27(2):73-82
Ewanick, S., Bura, R. and Saddler, J.N. (2007). Acid-catalyzed steam pretreatment of Lodgepole pine and subsequent enzymatic hydrolysis and fermentation to ethanol. -Biotechnology and Bioengineering 98(4):737-746
Tu, M., Chandra, R.P. and Saddler, J.N. (2007). Recycling Cellulases during the Hydrolysis of Steam Exploded and Ethanol Pretreated Lodgepole Pine -Biotechnology Progress, 23(5) 1130-1137
Berlin, A., Munoz, C., Gilkes, N., Massoumi Alamouti, S., Chung, P., Kang, K., Maximenko, V., Baeza, J., Freer, J., Mendoca, R. and Saddler, J.N. (2007). An Evaluation of British Columbian Beetle-Killed Hybrid Spruce for Bioethanol Productin --Applied Biochemistry and Biotechnology, 136-140:267-280
Berlin, A., Maximenko, V., Gilkes, N. and Saddler, J.N. (2007). Optimization of Enzyme Complexes for Lignocellulose Hydrolysis -Biotechnology and Bioengineering, 97(2):287-296
Ohgren, K., Bura, R., Lenicki, G., Saddler, J.N. and Zacchi, G. (2007). A comparison between simultaneous saccharification and fermentation and separate hydrolysis and fermentation using steam-pretreated corn stover -Process Biochemistry, 42(5):834-839
Pan, X.-J., Xie, D., Yu, R., Lam, D. and Saddler, J.N. (2007). Pretreatment of lodgepole pine killed by mountain pine beetle using organosolv ethanol process: fractionation and process optimization -Industrial & Engineering Chemistry Research, 46(8):2609-2617
Mabee, W.E., Fraser, E.D.G., McFarlane, P.N. and Saddler, J.N. (2007). Canadian biomass reserves for biorefining. Applied Biochemistry and Biotechnology 129 (1-3) 22-40.
Adamowicz, V., Boyda, A. and McFarlane, P.N. (2007): (2007). Global Wood Supply. Report #02 in the Series on “Drivers of Change in Canada’s Forests and Forest Sector”, prepared for the Forest Futures Project of the SFM Network, University of Alberta. 16 pp. November. --SFM Network, University of Alberta
Ohgren, K., Bura, R., Saddler, J.N. and Zacchi, G. (2006). Effect of hemicellulose and lignin removal on enzymatic hydrolysis of steam pretreated corn stover. -Bioresource Technology 93(13):2503-2510
Pan, X Ehara K. Gilkes, N. Kadla, J. F. Saddler J. (2006). Organosolv ethanol lignin from hybrid poplar as a radical scavenger: relationship between lignin structure, extraction conditions and antioxidant activity J. Agr. Food Chem. 54, 5806-5813, 2006.
Pan, X, Gilkes, N., Kadla, J., Pye, K., Saka, S., Ehara, K., Gregg, D., Xie, D., Lam, D. and Saddler, J. (2006). Bioconversion of hybrid poplar to ethanol and co-products using an organosolv fractionation Process: Optimization of process yields. Biotechnology and Bioengineering, published online, DOI:10.1002/bit.20905
Berlin, A., Balakshin, M., Gilkes, N., Kadla, J., Maximenko, V, Kubo, S. and Saddler, J.N. (2006). Inhibition of cellulase, xylanase and ß-glucosidase activities by softwood lignin preparations Journal of Biotechnology 125(2):198-209
Keating, J., Johansson, C., Saddler, J.N. and Beatson, R. (2006). The nature of chromophores in high extractive mechanical pulps: Western red cedar (Thuja plicata Donn) chemithermomechanical pulp (CTMP) Holzforschung 60:365-371
Tu, M., Zhang, X., Kurabi, A., Gilkes, N., Mabee, W. and Saddler, J.N. (2006). Immobilization of ß-glucosidase on Eupergit C for lignocellulose hydrolysis Biotechnology Letters. 28: 151-156
Pan, X.J., Gilkes, N. and Saddler, J. (2006). Effect of acetyl groups on enzymatic hydrolysis of cellulosic substates -Holzforschung, 94, 851-861
Berlin, A., Maximenko, V., Bura, R., Kang, K., Gilkes, N. and Saddler, J. (2005). A rapid microassay to evaluate enzymatic hydrolysis of lignocellulosic subtrates Wiley InterScience, published online, DOI: 10.1002/bit.20783
Berlin, A., Gilkes, N., Kurabi, A., Bura, R., Tu, M., Kilburn, D. and Saddler, J (2005). Weak lignin-binding enzymes - a novel approach to improve the activity of cellulases for hydrolysis of lignocellulosics Applied Biochemistry and Biotechnology, 121-124:163-170
Pan, X., Arato, C., Gilkes, N., Gregg, D.J., Mabee, W., Pye, E.K., Xiao, X. and Saddler, J.N. (2005). Biorefining of softwoods using ethanol organosolv pulping - preliminary evaluation of process streams for manufacture of fuel-grade ethanol and co-products. Biotechnology and Bioengineering. Vol. 90
Pan, X., Xie, D., Gilkes, N., Gregg, D.J. and Saddler, J.N. (2005). Strategies to enhance the enzymatic hydrolysis of pretreated softwood with high residual lignin content Applied Biochemistry and Biotechnology. Vol. 121-124
Alex Berlina, Neil Gilkesa, Douglas Kilburna, Renata Buraa, Alexander Markovb, Anton Skomarovskyb, Oleg Okunevc, Alexander Gusakovb, Vera Maximenkoa, David Gregga, Arkady Sinitsynb and John Saddler (2005). Evaluation of novel fungal cellulase preparations for ability to hydrolyze softwood substrates - evidence for the role of accesory enzymes - Enzyme and Microbial Technology Volume 37, Issue 2, 1 July 2005, Pages 175-184
Mabee, W.E., Gregg, D.J. and Saddler, J.N. (2004). International Energy Agency - Bioenergy. Current State of Fuel Ethanol Commercialization. Special Session B. Applied Biochemistry and Biotechnology. Vol 113-116
Cullis, I.F., Saddler, J.N. and Mansfield, S.D. (2004). Effect of initial moisture content and chip size on the bioconversion efficiency of softwood lignocellulosics. Biotechnology and Bioengineering, 85(4):413-421.
Xiao, Z., Zhang, X., Gregg, D.J. and Saddler, J.N. (2004). Effects of sugar inhibition on cellulase and B-glucosidase during enzymatic hydrolysis of softwood substrates. Applied Biochemistry and Biotechnology. Vol 113 - 116.(Proceedings of the 25th Symposium on Biotechnology for Fuels and Chemicals, May 2003)
Keating, J.D., Robinson, J., Bothast, R.J., Saddler, J.N. and Mansfield, S.D. (2004). Characterization of a Unique Ethanologenic Yeast Capable of Fermenting Galactose. Enzyme and Microbial Technology. 35(2/3):242-253
Keating, J. D., Robinson, J., Cotta, M. A., Saddler, J. N., and Mansfield, S. D. (2004). An Ethanologenic Yeast Exhibiting Unusual Metabolism in the Fermentation of Lignocellulosic Hexose Sugars Industrial Microbiology and Biotechnology. 31(5):235-244
Stebbing, D.W., Zhang, X., Soong, G., Mansfield, S.D. and Saddler, J.N. (2004). Fungal enzyme treatment of newsprint mill white water – impact on water and fiber properties. Pulp and Paper Science, Vol. 30. No. 1:3-8
Keating, J., Johansson, I., Saddler, J.N., and Beatson, R.P. (2004). Kinetics and Mechanism of Hydrogen Peroxide Brightening of Western Red Cedar CTMP Paper being presented at PAPTAC (Pulp and Paper Technical Association of Canada) Conference in Parksville, BC on April 16 and 17, 2004
Saddler, J.N., Gregg, D.J. and Mabee, W.E. (2004). Progress in the Commercialization of Lignocellulosics-to-Ethanol Paper being presented at the 2nd World Conference and Technology Exhibition on Biomass for Energy, Industry and Climate Protection, May 2004.
Mansfield, S.D. and Saddler, J.N. (2003). Application of Enzymes to Lignocellulosics American Chemical Society - Oxford University Press
O''Connor, D., Esteghlalian, A.R., Gregg, D.J. and Saddler, J.N. (2003). Carbon Balance of Ethanol from Wood: The effect of Feedstock Source in Canada. The Role of Boreal Forests and Forestry in the Global Carbon Budget. pp. 289-296 (Proceedings of the International Science Conference, Edm. Alta. May 2000)
Bura, R., Bothast, R.J., Mansfield, S.D. and Saddler, J.N. (2003). Optimization of SO2-Catalysed Steam Pretreatment of Corn Fibre for Ethanol Production Applied Biochemistry and Biotechnology, Vol. 105-108: 319-335.
Robinson, J., Keating, J.D., Mansfield, S.D. and Saddler, J.N. (2003). The fermentability of concentrated softwood derived hemicellulose fractions with and without supplemental cellulose hydrolysates. Enzyme and Microbial Technology, 33(6), 757-765.
Graham, P.J., Gregg, D.J. and Saddler, J.N. (2003). Wood-Ethanol for Climate Change Mitigation in Canada Applied Biochemistry and Biotechnology Vol. 105-108. (Proceedings of the 24th Symposium on Biotechnology for Fuels and Chemicals, May 2002)
Himmel, M.D., Baker, J.O. and Saddler, J.N., Editors (2003). Glycosyl Hydrolases for Biomass Conversion ACS Symposium Series 769
Mais, U., Esteghlalian, A.R. and Saddler, J.N. (2002). Influence of Mixing Regime on Enzymatic Saccharification of Steam-Exploded Softwood Chips. Applied Biochemistry and Biotechnology, Vol 98-100, 463-472. (Proceedings of the 23rd Symposium on Biotechnology for Fuels and Chemicals, Colorado, May 2001)
Robinson, J., Keating, J., Boussaid, A., Mansfield, S.D. and Saddler, J.N. (2002). The influence of bark on the fermenation of douglas-fir whitewood pre-hydrolysates Applied Microbiology and Biotechnology. 59 (4-5): 443-448
Esteghlalian, A.R., Mansfield, S.D. and Saddler, J.N. (2002). Cellulases: Agents for Fiber Modification or Bioconversion? The effect of substrate accessibility on cellulose enzymatic hydrolyzability. L. Viikari & R. Lantto (Eds.), Biotechnology Progress, Vol. 21, pp. 21-36. Elsevier Science.
Saddler, J., R.A. Kozak and S. Watts (2002). A University Perspective on Innovations in Forestry Science and Technology. The Forestry Chronicle 78(1):115-116.
Zhang, X., Stebbing, D.W., Soong, G, Saddler, J.N. and Beatson, R.P. (2002). A combined fungal and enzyme treatment system to remove TMP/newsprint mill white waters substances. TAPPI 1(2):21-27.
Bura, R., Mansfield, S.D., Saddler, J.N. and Bothast, R.J. (2002). SO2-catalysed steam explosion of corn fibre for ethanol production. Applied Biochemistry and Biotechnology 98(100):59-72.
Lu, Y., Yang, B, Gregg, D.J., Saddler, J.N. and Mansfield, S.D. (2002). Cellulase adsorption and an evaluation of enzyme recycle during the hydrolysis of steam-exploded softwood residues. Applied Biochemistry and Biotechnology, Vol. 98-100, 641-654.
Mais, U., Esteghlalian, A.R., Saddler, J.N. and Mansfield, S.D. (2002). Enhancing the enzymatic hydrolysis of cellulosic materials using simultaneous ball milling. Applied Biochemistry and BiotechnologyVol 98-100, 815-832.
Yang, B., Boussaid, A., Mansfield, S.D., Gregg, D.J. and Saddler, J.N. (2002). A fast and efficient alkaline peroxide treatment to enhance the enzymatic digestibility of steam exploded softwood substrates. Biotechology and Bioengineering 77(6):678-684.
Zhang, X., Eigendorf, G., Stebbing, D.W., Mansfield, S.D. and Saddler, J.N. (2002). Degradation of trilinolein by laccase enzymes. Archives of Biochemistry and Biophysics. 405(1):44-54.
Esteghlalian, A., Graham, P., Gregg, D.J., O''''Connor, D. and Saddler, J.N. (2002). The Potential of Short Rotation Forestry on Marginal Farmland in BC and Alberta to Provide a Feedstock for Energy Generation and to Reduce Greenhouse Gas Emissions Suststainable Forest Management Network (Final project report 2002-5)
Esteghlalian, A.R., Bilodeau, M., Mansfield, S.D.and Saddler, J.N.. (2001). Do enzymatic digestibility and Simons' stain reflect the differences in the available surface area of lignocellulosic substrates. Biotechnology Progress 17:1049-1054.
Boussaid, A., Cai Y., Robinson, J., Gregg, D.J., Nguyen, Q. and Saddler, J.N. (2001). Sugar recovery and fermentability of hemicellulose hydrolysates from steam-exploded softwoods containing bark. Biotechnology Progress 17(5):887-892.
Ingesson, H., Zacchi, G., Yang, B., Esteghlalian, A.R. and Saddler, J.N. (2001). The effect of shaking regime on the rate and extent of enzymatic hydrolysis of cellulose. Biotechnology 88:177-182.
Esteghlalian, A.R., Srivastava, V., Gilkes, N.R., Kilburn, D.G., Warren, R.A.J. and Saddler, J.N. (2001). Do Cellulose Binding Domains Increase Substrate Accessibility? Applied Biochemistry and Biotechnology, Vol. 91-93, 575-592 (Proceedings of the 22nd Symposium on Biotechnology for Fuels and Chemicals, Tenessee, May 2000)
S.M. Shevchenko, L. Pazner, J.N. Saddler (2001). Treatment of Organosolov and Steam Explosion Lignins with Molecular Hydrogen Iodide: A Structural Probe Cellulose Chemistry and Technology. Vol 35, 3-4, 295-318
Saddler, J.N., Zhang, X., Beatson, R.P., Stebbing, D.W., Cai, Y., Soong, JJ. (2001). Enzymatic and Microbial Treatment of Concentrated and Recycled Pulp Effluents Sustainable Forest Management Network (Final project report 2001-21)
Johannsson, C.I., Saddler, J.N. and Beatson, R.P. (2000). Characterization of the Polyphenolics Related to the Colour of Western Red Cedar (Thuja plicata Donn) Heartwood Holzforschung 54(3): 246-254
Johansson, I., Beatson, R.P. and Saddler, J.N. (2000). Fate and Influence of Western Red Cedar Extractivesin Mechanical Pulping. Wood and Fibre Science 34(5): 389-401
Shevchenko, S., Paszner, L. and Saddler, J.N. (2000). Structural Changes in Lignin During Organosolv Pulping and Steam Explosion as Evidenced by Mild Depolymerization with Molecular Hydrogen Iodide. In press. Cellulose Chemistry and Technology 35 (5/6)
Zhang, X., Stebbing, D.W., Saddler, J.N., Beatson, R.P. and Kruus, K. (2000). Enzyme Treatments of the Dissolved and Colloidial Substances Present in Mill White Water and the Effects on the Resulting Paper Properties. Journal of Pulp and Paper Science. 3(20) pp. 321-335
Saddler, J.N. (2000). The Potential of Western Red Cedar as a Furnish for High Quality Mechanical Pulps. Wood and Fibre Science
Esteghlalian, A., Boussaid, A., Gregg, D.J., Lee, K.H., Saddler, J.N., (2000). Steam Pretreatment of Douglas-Fir Wood Chips: Can Conditions for Optimum Hemicellulose Recovery Still Privide Adequate Access for Efficient Enzymatic Hydrolysis? Applied Biochemistry and Biotechnology (Proceedings of the 21st Symposium on Biotechnology for Fuels and Chemicals, Colorado, May 1999)
Esteghlalian, A., Srivastava, V., Gilkes, N., Gregg, D.J.and Saddler, J.N. (2000). An Overview of Factors Influencing the Enzymatic Hydrolysis of Lignocellulosic Feedstocks. ACS Series X, Ed. M. Himmel, J. Baker and J.N. Saddler.
Esteghlalian, A.R., Srivastava, V., Gilkes, N.R., Kilburn, D.G., Warren, R.A.J. and Saddler, J.N. (2000). Interaction Between Cellulose and a Cellulose-Binding Domain (CBDCex) From Bacterium Cellulomonas fimi and Its Effect on Substrate Enzymatic Susceptibility. NREL Proceedings of the Twenty-second Symposium on Biotechnology for Fuels and Chemicals.
Shevchenko, S.M., Chang, K., Robinson, J. and Saddler, J.N. (2000). Optimization of monosaccharide recovery by post-hydrolysis of the water-soluble hemicellulose component after steam explosion of softwood chips. Bioresource Technology 72(3): 207-211.
Serreqi, A., Gamboa, H., Stark, K., Saddler, J.N. and Breuil, C.. (2000). Resin acid markers for total resin acid content in-mill process lines of a TMP/CTMP pulp mill. Water Research 34(5):1727-1733.
Mansfield, S.D. and Saddler, J.N. (1999). Sheet properties of Douglas-fir kraft pulp after selective treatments of different fibre length fractions with cellulases. Pulp and Paper Science 25(3): 84-89.
Mansfield, S.D., Swanson, D.J., Roberts, N., Olson, J.A. and Saddler, J.N. (1999). Enhancing Douglas-fir pulp properties with a combination of enzyme treatments and fiber fractionation. Tappi. 82(5):152-158.
Mooney, C.A., Mansfield, S.D., Beatson, R.P. and Saddler, J.N. (1999). The effect of fiber characteristics on hydrolysis and cellulase accessibility to softwood substrates. Enzyme Microbilogy Technology. 25(8-9): 644-650.
Gübitz, G.M., C.D. Edgar, S.D. Mansfield, J.N. Saddler, and W. Steiner. (1999). Role of cellulase/hemicellulase synergism in the modification of pretreated wood substrates. Int'l Symp. Biotechnol. Lignocell. Mat. Curitiba, Brazil. pp. 45-56.
Wu, M.M., Chang, K., Gregg, D.J., Boussaid, A., Beatson, R. P. and Saddler, J.N. (1999). Optimization of steam explosion to enhance hemicellulose recovery and enzymatic hydrolysis of softwoods. Applied Biochemistry and Biotechnology. Vol. 77-79: 47-54. (Proceedings of the 20th Symposium on Biotechnology for Fuels and Chemicals, Tennessee, May, 1998)
Zhang, X., Beatson, R.P., Cai, Y.J. and Saddler, J.N. (1999). Accumulation of specific dissolved and colloidal substances during white water recycling affects paper properties. Pulp and Paper Science. Vol. 25(6):206-210.
Lee, D., A.H.C. Yu and J.N. Saddler. 1996 (1999). Effect of lignin on cellulose recycling strategies. pp. 547-550 in E. Srebotnik and K. Messner (eds.), Advances in Applied and Fundamental Research. Proc. 6th Int'l Conf. on Biotechnology in the Pulp and Paper Industry.
Beatson, R.P., X. Zhang, D. Stebbing, and J. Saddler. (1999). The dissolved and colloidal fractions of white water: Impact of paper properties and degradation by enzymes. -Vol. 1:200-203 in 10th Int'l Symp. on Wood and Pulp Chemistry, Yokohama, Japan.
Boussaid, A. and Saddler, J.N.. (1999). Adsorption and activity profiles of cellulases during the hydrolysis of two Douglas-fir pulps. Enzyme and Microbiology Technology. 24 (3-4):138-143.
Boussaid, A., Robinson, J., Cai, Y.J., Gregg, D.J. and Saddler, J.N. (1999). Fermentability of the hemicellulose-derived sugars from steam-exploded softwood (Douglas-fir). Biotechnology and Bioengineering 64(3): 284-289
Chandra, R.P., Beatson, R.P., de Jong, E. and Saddler, J.N. (1999). The Effects of Treatment with the White Rot Fungus Trametes Versicolor and Laccase Enzymes on the Brightness of Douglas-Fir Heartwood Derived Thermomechanical Pulps. Wood Chemistry and Technology. 19(1-2): 61-78.
Lumme, M.S., Mansfield, S.D. and Saddler, J.N. (1999). The effects of hydrolytic enzyme treatments on three British Columbian interior fir kraft pulps differing in their initial fiber coarseness. Wood and Fiber Science. 31(4): 385-393.
Mansfield, S.D., Mooney, C. and Saddler, J.N. (1999). Substrate and enzyme characteristics that limit cellulose hydrolysis. Biotechnology Progress. 15(5): 804-816.
Ramos, L.P., Filho, A.Z., Deschamps, F.C. and Saddler, J.N.. (1999). The effect of trichoderma cellulases on the fine structure of a bleached softwood kraft pulp. Enzyme and Microbiology Technology. 24:371-380.
Saddler, J.N., X. Zhang, D. Stebbing, R.P. Beatson, B.G. Chalmers, and J.T. Ling. (1999). The different effects of white water dissolved and colloidal fractions on paper properties and effects of enzyme treatments on their removal. PACWEST, Whistler. pp. 18-24.
Shevchenko, S.M., Beatson, R.P. and Saddler, J.N. (1999). The nature of lignin from steam explosion/enzymatic hydrolysis of softwood: Structural features and possible uses. Applied Biochemistry and Biotechnology. Vol. 77-79: 867-876. (Proceedings of the 20th Symposium on Biotechnology for Fuels and Chemicals, Tennessee, May 1998)
Stalbrand, H., S.D. Mansfield, J.N. Saddler, D.G. Kilburn, R. Anthony J. Warren, and N.R. Gilkes. (1998). Analysis of molecular size distributions of cellulose during hydrolysis of cellulose by recombinent cellulomonas fimi Beta-1, 4-glucanases. App. Environ. Microbiol. 64(7):2374-2379.
Gregg, D.J., A. Boussaid and J.N. Saddler. (1998). Technoeconomic evaluations of a generic wood-to-ethanol process: Process effect of increased cellulose yields and enzyme recycle. Bioresource Technol. 63(1998):7-12.
Gubitz, G.M., D.W. Stebbing, C.I. Johansson, and J.N. Saddler. (1998). Lignin-hemicellulose-complexes restrict enzymatic solubilisation of mannan and xylan from dissolving pulp. Appl. Microbiol. Biotechnol. 50:390-395.
Gubitz, G.M., S.D. Mansfield, D. Bohm, and J.N. Saddler. (1998). Effect of endoglucanases and hemicellulases in magnetic and flotation deinking of xerographic and laser-printed papers. Journal of Biotechnology 65:209-215.
Kyriacou, P., E. de Jong, C. Johansson, R.P. Chandra, and J.N. Saddler. (1998). Bleaching of western red cedar and Douglas-fir mechanical pulps. TAPPI J. 81(6):188-195.
Mansfield, S.D., J.N. Saddler and G.M. Gubitz. (1998). Characterisation of two endoglucanases from the brown-rot fungi Gloeophyllum sepiarium and Gloeophyllum trabeum. Enzyme Microb. Technol. 23:133-140.
Ryan, S.E., E. de Jong, G.M. Gubitz, M. Tuohy, and J.N. Saddler. (1998). The potential of hydrolytic enzymes to modify Douglas-fir derived bleached mechanical pulps. The Royal Society of Chemistry. pp. 214-226 in Claeyssens, M. et al. (eds.), Carbohydrases from T. reesei and other microorganisms.
Gübitz, G.M., S.D. Mansfield and J.N. Saddler. (1998). Effectiveness of two endoglucanases from Gloeophyllum sp. in deinking mixed office waste. 7th International conference on Biotechnology in the Pulp and Paper Industry. June 16-19, 1998. Vancouver, BC. CPPA 3:135-138.
Lumme, M.S., S.D. Mansfield, and J.N. Saddler. (1998). Effect of enzyme treatment on two British Columbia interior fir kraft pulps. 7th International conference on Biotechnology in the Pulp and Paper Industry. June 16-19, 1998. Vancouver, BC. CPPA 3:163-166.
Mansfield, S.D., A.R. Dickson, and J.N. Saddler. (1998). Improving paper properties by a selective enzymatic treatment of coarse pulp fibres. 7th International conference on Biotechnology in the Pulp and Paper Industry. June 16-19, 1998. Vancouver, BC. CPPA 1:189-192.
Mansfield, S.D., B. Saake, G.M. Gübitz, E. de Jong, J. Puls, and J.N. Saddler. (1998). Identification, purification and characterisation of the predominant endoglucanases from two brown-rot fungal strains of Gloeophytllum. pp. 227-244 in Proc. 1997 Tricel Symp. Ghent, Belgium.
Mooney, C.A., S.D. Mansfield, R.P. Beatson, and J.N. Saddler. (1998). The effect of fibre characteristics on accessibility and hydrolysis of softwood substrates. 7th International conference on Biotechnology in the Pulp and Paper Industry. June 16-19, 1998. Vancouver, BC. CPPA 3:99-102.
Mooney, C.A., S.D. Mansfield, M.G. Touhy, and J.N. Saddler. (1998). The effect of initial pore volume and lignin content on the enzymatic hydrolysis of softwoods. Bioresource Technol. 64(2):113-119.
Edgar, C.D., S.D Mansfield, G.M. Gübitz, and J.N. Saddler. (1998). The synergistic effects of endoglucanase and xylanase in modifying Douglas-fir kraft pulp. Oxford University Press. pp.75-87 in Eriksson, K.-E. L and Cavaco-Paulo, A.M. (eds.), Enzyme Applications in Fibre Processing.
Mansfield, S.D. and J.N. Saddler. (1997). The use of enzymes to enhance Douglas-fir pulp characteristics. 1997 TAPPI Biological Sciences Symposium. October 19-23, 1997. San Francisco, CA. TAPPI Press 1:279-282.
Mansfield, S.D., E. de Jong and J.N. Saddler. (1997). The potential of enzymes to selectively modify pulp characteristics. In Proc. '97 Spring Conf. of CPPA Pacific Coast and Western Branches, Whistler Paper 3B:1-4.
Mansfield, S.D., E. de Jong, R.S. Stephens, and J.N. Saddler. (1997). Physical characterization of enzymatically modified kraft pulp fibres. J. Biotechnol. 57(1-3): 205-216.
Mooney, C.A., S.D. Mansfield, M.G. Touhy, and J.N. Saddler. (1997). The effect of lignin content on cellulose accessibility and enzymatic hydrolysis of softwood pulps. 1997 TAPPI Biological Sciences Symposium. October 19-23, 1997. San Francisco, CA. TAPPI Press 1:259-265.
Zhang, Y., P.A. Bicho, C. Breuil, J.N. Saddler, and S.N. Liss. (1997). Resin acid degradation by bacterial strains grown on CTMP effluent. Water Sci. Tech. 35:33-39.
Saddler, J.N. and D.J. Gregg. (1997). Steam explosion and bioconversion of softwoods. pp. 135-138 in M. Stumborg (ed.), Proc. '97 Ethanol Research and Development Workshop, Ottawa.
Gregg, D.J. and J.N. Saddler. . (1997). A review of techno-economic modelling methodology for a wood-to-ethanol process. In Proc. 18th Symp. Biotechnology for Fuels and Chemicals. Appl. Biochem. Biotechnol. 63/65:609-623
Liss, S.N., P.A. Bicho, P.N. McFarlane, and J.N. Saddler. (1997). Microbiology and biodegradation of resin acids in pulp mill effluents: A mini review. Can. J. Microbiol. 75:599-611.
Wong, K.K.Y., L.A. Martin, F.M. Gama, J.N. Saddler, and E. de Jong. (1997). Bleach boosting and direct brightening by multiple xylanase treatments during peroxide bleaching of Kraft pulps. Biotechnol. Bioengin. 54:312-318.
Li, K., A. Serreqi, C. Breuil and J.N. Saddler. (1997). Quantification of resin acids in CTMP effluents using an enzyme-linked immunosorbent assay. Water Science & Technol. 35(2-3):93-99.
de Jong, E., K.K.Y. Wong, and J.N. Saddler. (1997). The mechanism of xylanase prebleaching of kraft pulp - an examination using model pulps prepared by depositing lignin and xylan on cellulose fibers. Holzforschung 51:19-26.
Gregg, D.J. and J.N. Saddler. (1997). The IEA network: Biotechnology for the conversion of lignocellulosics. pp. 55-60 in Proc. 2nd European Motor Biofuels Forum, Graz, Austria.
de Jong, E., K.K.Y., L.R. Windsor, and J.N. Saddler. (1996). Xylanase prebleaching of model pulp. Proc. 6th Int'l Conf. on Biotechnology in the Pulp and Paper Industry. pp. 127-130 in E. Srebotnik and K. Messner (eds.), Advances in Applied and Fundamental Research.
Gregg, D. and J.N. Saddler. (1996). Factors affecting cellulose hydrolysis and the potential of enzyme recycle to enhance the efficiency of an integrated wood-to-ethanol process. Biotech/Bioeng. 51:375-383.
Gregg, D. and J.N. Saddler. (1996). A technoeconomic assessment of the pretreatment and fractionation steps of a biomass-to-ethanol process. Appl. Biochem. Biotechnol. 57/58:711-727.
Mansfield, S.D., K.K.Y. Wong, E. de Jong, and J.N. Saddler. (1996). Xylanase prebleaching of different fiber length fractions of Douglas-fir kraft pulp. Appl. Microbiol. & Biotechnol. 46:319-326.
Mansfield, S.D., K.K.Y. Wong, T. Astle, and J.N. Saddler. (1996). Enzymatic modification of coarse pulp fibers derived from Douglas-fir. pp. 173-176 in E. Srebotnik and K. Messner (eds.), Advances in Applied and Fundamental Research. Proc. 6th Int'l Conf. on Biotechnology in the Pulp and Paper Industry.
Mansfield, S.D., K.K.Y. Wong, E. de Jong, and J.N. Saddler. (1996). Modification of Douglas-fir mechanical and kraft pulps by enzymatic treatment. Tappi J. 79(8):125-132.
Bicho, P.A., V.A. Martin and J.N. Saddler. (1996). Resin acid biodegradation by bacteria isolated from bleached kraft mill effluent: Specificity and induction. pp. 611-616 in E. Srebotnik and K. Messner (eds.), Advances in Applied and Fundamental Research. Proc. 6th Int'l Conf. on Biotechnology in the Pulp and Paper Industry.
Bullock, C.M., P.A. Bicho, and J.N. Saddler. (1996). The influence of the high and low molecular weight fractions on the microbial activity of activated sludge. Water Research 30(5):1095-1102.
Bullock, C.M., P.A. Bicho, Y. Zhang, and J.N. Saddler. (1996). A solid chemical oxygen demand (COD) method for determining biomass in waste waters. Water Research 30(5):1280-1284.
Werker, A.G., P.A. Bicho, J.N. Saddler, and E.R. Hall. (1996). Surface tension changes related to the biotransformation of dehydro-abietic acid by Mortierella isabellina. pp. 139-150 in M.R. Servos (ed.), Environmental Fate and Effects of Pulp and Paper Mill Effluents. St. Lucie Press.
Wong, K.K.Y., E. de Jong, and J.N. Saddler. (1996). Size-exclusion chromatography of lignin- and carbohydrate-containing samples using alkaline effluents. J. Chromatography A 737:193-203.
Wong, K.K.Y., E. de Jong, and J.N. Saddler. (1996). Lignin-xylan complexes in kraft pulp appear to be target substrates for xylanase prebleaching. Proc. 6th Int'l Conf. on Biotechnology in the Pulp and Paper Industry. pp. 93-98 in E. Srebotnik and K. Messner (eds.), Advances in Applied and Fundamental Research.
Wong, K.K.Y., S.L. Nelson, and J.N. Saddler. (1996). Xylanase treatment for the peroxide bleaching of oxygen delignified kraft pulps derived from three softwood species. J. Biotechnol. 48:137-145.
Wong, K.K.Y., S. Yokota, J.N. Saddler, and E. de Jong. (1996). Enzymatic hydrolysis of lignin-carbohydrate complexes isolated from kraft pulps. J. Wood Chem. Technol. 16(2): 121-138.
Li, K., T. Chen, P. Bicho, C. Breuil, and J.N. Saddler. (1996). Factors affecting gas chromatographic analysis of resin acids present in pulp mill effluents. Toxicological and Environm. Chem. 57:1-16.
Bicho, P.A., T. Chen, S. Avramidis, R.L. Zwick, C. Breuil, and J.N. Saddler. (1996). Characterization and treatment of condensates generated from radio-frequency/vacuum dried softwoods. For. Prod. J. 46(10):51-56.
Li, K., T. Chen, P. Bicho, C. Breuil, and J.N. Saddler. (1996). A comparison of gas chromatographic and inununochemical methods for quantifying resin acids. St. Lucie Press. pp. 119-128 in Servos el al. (eds.), Environmental Fate and Effects of Pulp and Paper Mill Effluents.
Nelson, S.N., K.K.Y. Wong, R.P. Beatson, and J.N. Saddler. (1995). The use of xylanase for peroxide bleaching of kraft pulps derived from different softwood species. Pulp and Paper Canada 96(7):42-45.
Nelson, S., K.K.Y. Wong, R.P. Beatson, and J.N. Saddler. (1995). Xylanase prebleaching of brownstock and oxygen delignified kraft pulp derived from Douglas-fir. pp. 413-418 in Proc. IWC Meeting, Helsinki.
Werker, A.G., P.A. Bicho, J.N. Saddler, and E.R. Hall. (1995). Surface tension changes related to the biotransformation of dehydroabietic acid by Mortierella isabellina. pp. 134-137 in Servos et al. (eds.), Environmental Fate and Effects of Pulp and Paper Mill Effluents. St. Lucie Press.
Yokotu, S., K.K.Y. Wong, J.N. Saddler, and I.D. Reid. (1995). Molecular weight distribution of xylan/lignin mixtures from kraft pulps. Pulp & Paper Canada 96(4):39-41.
Yu, A.H.C. and J.N. Saddler (1995). Identification of essential cellulase components in the hydrolysis of a steam-exploded substrate Biotechnol. Appl. Biochem. 21:185-202.
Yu, A.H.C., D. Lee and J.N. Saddler (1995). Adsorption and desorption of cellulase components during hydrolysis of a steamexploded birch substrate. Biotechnol. Appl. Biochem. 21:203-216.
Bicho, P.A., V. Martin, and J.N. Saddler. (1995). Growth, induction and substrate specificity of dehydroabietic acid degrading bacteria isolated from a kraft mill effluent enrichment. Appl. Environ. Microbiol. 61(9):3245-4350.
Gregg, D. and J.N. Saddler. (1995). Bioconversion of lignocellulosic residues to ethanol: process flowsheet development. Biomass and Bioenergy 9:287-302.
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